Biosensors For the Measurement of C-Terminal Telopeptide of Type I Collagen (CTX-I)

In the last few years, research on the use of biochemical markers of bone turnover has greatly improved. Among the several available bone turnover markers, monitoring serum C-terminal cross-linked telopeptides is one of the most accurate one.

Manual and automated immunoassays are available for the measurement of CTX, which show high analytical performance. However, they are very expensive, time-consuming and require technical experts to perform the CTX assay.

Different research groups have proposed novel immunosensing methods to detect CTX biomarker. It is a hope that the development of a rapid and inexpensive point-of-care device can aid in monitoring the bone metabolism more frequently, which can be helpful in indicating the early stages of bine loss.

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Extensor Tendon Injury in the Distal Forearm of Right Hand Owing to Accident

A Bangladeshi 24 year old man was admitted to the hospital with a right hand injury. The examination showed that the tendons of the right hand of the patient were severely injured.

X-ray report showed no bone injury. Within 24 h of the accident surgery was performed but the patient was unable to move the thumb. Therefore a second time surgery was performed.

In the second surgery extensor carpi radialis longus (ECRL), extensor carpi radialis brevis (ECRB), abductor pollicis brevis (APB), extensor pollicis brevis (EPB) were found defected and all separated tendons were repaired effectively.

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Extensor Tendon Injury in the Distal Forearm of Right Hand Owing to Accident

A Bangladeshi 24 year old man was admitted to the hospital with a right hand injury. The examination showed that the tendons of the right hand of the patient were severely injured.

X-ray report showed no bone injury. Within 24 h of the accident surgery was performed but the patient was unable to move the thumb. Therefore a second time surgery was performed.

In the second surgery extensor carpi radialis longus (ECRL), extensor carpi radialis brevis (ECRB), abductor pollicis brevis (APB), extensor pollicis brevis (EPB) were found defected and all separated tendons were repaired effectively.

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Rheumatoid Arthritis and Osteoporosis: A Case Study

Metadichol is a Nano emulsion of long-chain alcohols called as Policosanol and is present in foods such as rice, sugar cane, wheat, and peanuts. Metadichol acts on Nuclear Vitamin D receptors (VDR) that are present in cells throughout the body to stimulate the immune system and inhibit a variety of disease processes, resulting from inflammation to infection.

We present a case study of a patient with Rheumatoid arthritis with the high levels of RF antibodies, CRP and ESR levels, and low bone mineral density leading to osteoporosis. The case report shows how Metadichol by its actions on the VDR has affected key biomarkers and mitigated the disease conditions without any side effects. Also, his bone density improved dramatically.

Metadichol is safe because it consists of natural components of conventional foods and has no known adverse side effects. Its constituents are present in many foods that we consume every day.

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Rheumatoid Arthritis and Osteoporosis: A Case Study

Metadichol® is a Nano emulsion of long-chain alcohols called as Policosanol and is present in foods such as rice, sugar cane, wheat, and peanuts.

Metadichol® acts on Nuclear Vitamin D receptors (VDR) that are present in cells throughout the body to stimulate the immune system and inhibit a variety of disease processes, resulting from inflammation to infection.

We present a case study of a patient with Rheumatoid arthritis with the high levels of RF antibodies, CRP and ESR levels, and low bone mineral density leading to osteoporosis.

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Rocuronium as Selective Local Musclerelaxant in Orthopedic Surgery

A variety of surgeries need profound muscular block solely in an exceedingly restricted surgical field. Recent accessibility of sugammadex, a cyclodextrin derivative antitoxic substance active on an amino steroid muscle relaxant, has offered the likelihood of maintaining a prolonged deep neuromuscular paralysis with a rapid reversal at the end of surgery.

As a consequence, complete post anesthesia recovery is often rapidly obtained under safe clinical conditions.

However, in selected patients, a muscle relaxant can be locally injected at low doses in one or more muscles concerned within the surgical technique without a systemic paralysis.

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Non-typhoidal Salmonella Osteomyelitis of the Femoral Neck in an Immunocompetent Child

We report a case of Salmonella osteomyelitis of the femoral neck in a healthy child. Such an occurrence in an immunocompetent child is extremely rare and has not yet been reported in the English literature.

Salmonella should be considered among the causative agents in acute osteomyelitis. Prompt antibiotic treatment is pivotal for preventing complications and decreasing the disease burden.

The non-typhoidal Salmonella serotype (NTSS) is one of the most important enteric pathogens in Taiwan, which most often results in self-limited acute gastroenteritis. However, approximately 5-7.6% of patients develop bacteremia.

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