65 Rheumatoid
Arthritis (RA) patients, 22 Osteoarthritis (OA) patients, and 40 sex and age
matched healthy donors were enrolled in this study.
Synovial
fluids mononuclear cells (SFMC) and peripheral blood mononuclear cells
(PBMC) were prepared by using Ficoll-Hypaque separation procedure.
Super Array
analysis was used to measure the expression profile of immune-related genes in
RA synovial tissues (RA-ST) and in normal PBMC treated with recombinant human
IL-18 binding protein a (IL-18BPa).
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