Primary systemic amyloidosis with main bone
involvement is a rare disease. Clinical symptoms and radiographic findings are
usually nonspecific and may be confused with primary bone tumor, metastatic
disease, metabolic disorders or infections. The occurrence of an amyloidoma in
the spine is rare.
We describe the case of a 57-year old man
presenting with a pathological fracture of T7 in presence
of a large, soft tissue mass narrowing the spinal canal, responsible for a
worsening paraplegia.
Diagnosis of systemic amyloidosis was made
after surgical treatment. Pathological examination showed an amorphous
eosinophilic material, positive staining with Congo red, birefringence under
polarized light relating to amyloid, with the presence of rare plasma cells.
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